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更新于 7月11日

(Senior) Research Scientist in vivo pharmacology體內(nèi)藥理

1.5-2.5萬(wàn)
  • 上海浦東新區(qū)
  • 3-5年
  • 本科
  • 全職
  • 招1人

職位描述

新藥
Job Responsibilities: ? Responsible for leading and carrying out in vivo pharmacology experiments, and supporting the company's R & D projects; ? Responsible for the management and maintenance of laboratory animals, including transgenic mice breeding, health monitoring and the quality control of experimental environment; ? Cooperate with team members to carry out anixperiment operations, ensure that the standard experimental operation procedures (SOPs) and animal welfare are strictly followed during experiments, and ensure the accuracy and reliability of experimental data; ? Participate in the design and implementation of in vivo pharmacological experiments, including selecting appropriate animal models, determining test indicators and methods, evaluating the efficacy, pharmacokinetics, safety, mechanism of action and toxicological properties of drugs, and providing key experimental basis and decision support for preclinical development of drugs; ? Collect experimental data timely and accurately during the experiments, including but not limited to the physiological indicators, histopathological changes, pharmacokinetic parameters, etc; ? Work closely with teams of medicinal chemistry, biology, toxicology, preclinical development and etc. as the main personnel of in vivo pharmacological research, to jointly promote the overall process of drug research and development projects. ? Keep up with the development trends in the field of in vivo pharmacology, actively develop and introduce new experimental technologies and methods, constantly optimize and improve existing research platforms, and improve research efficiency and data quality. Job requirements: 1. Work conscientiously and actively, have a positive attitude, have a sense of responsibility and self-improvement, can solve problems independently, be good at communication, have strong learning ability, clear thinking, strong adaptability, have a good team spirit, and have good English reading, writing and communication skills. 2. Research Scientist: i) Junior college or BS in Biology, Pharmacology, Veterinary, Biochemistry or related fields, II) At least 2 years of hands-on experience in rodents in vivo pharmacology experiments, proficient in various conventional administration methods, and familiar with animal tissue sample collection. III) Extended experience of transgenic mice breeding, maintaining and genotyping is preferred. 3. Senior Scientist: i) MS in biology, pharmacology, biochemistry, neurobiology, etc, II) At least 5 years of experience in pharmacological and pharmacodynamic experiments, especially neuropsychiatric pharmacological and pharmacodynamic experience, III) Familiar with the experimental operation related to anixperiments, with rich experience in the management of pharmacological and pharmacodynamic projects, IV) Extended experience in neuropharmacology, behavioural experiments and in vitro experiments is preferred.

工作地點(diǎn)

上海浦東新區(qū)ATLATL創(chuàng)新研發(fā)中心

職位發(fā)布者

劉薇/HR

昨日活躍
立即溝通
公司Logo維泰瑞隆
維泰瑞?。ū本┥锟萍加邢薰臼且患胰蛐缘膶W⒂谘邪l(fā)First-in-class化學(xué)藥物的生物制藥公司。該公司由北京生命科學(xué)研究所的所長(zhǎng),美國(guó)科學(xué)院院士,中國(guó)科學(xué)院外籍院士王曉東博士和北京生命科學(xué)研究所資深研究員張志遠(yuǎn)博士共同創(chuàng)建。公司坐落在昌平區(qū)中關(guān)村生命科學(xué)園。本公司針對(duì)王曉東博士在細(xì)胞凋亡、細(xì)胞程序性壞死等多種細(xì)胞死亡領(lǐng)域的原創(chuàng)性發(fā)現(xiàn)研發(fā)小分子抑制劑,致力于多種重大疾病的治療。這些抑制劑針對(duì)的疾病包括神經(jīng)退行性疾病如阿爾茲海默癥、多發(fā)性硬化癥、帕金森病等;缺血性疾病如腦卒中、腎缺血、心肌缺血;以及炎癥性疾病如腸炎、銀屑病、膿毒癥等。本公司研發(fā)能力涵蓋小分子篩選,化學(xué)合成,分子、細(xì)胞生物學(xué)研究,動(dòng)物藥效評(píng)價(jià),藥代藥動(dòng)分析及臨床前預(yù)毒理分析等藥物研發(fā)的所有環(huán)節(jié)。本公司的研發(fā)團(tuán)隊(duì)由王曉東博士和張志遠(yuǎn)博士直接領(lǐng)導(dǎo),團(tuán)隊(duì)主要成員均具備十年以上科學(xué)研究經(jīng)驗(yàn),前期科研成果均發(fā)表在國(guó)際頂級(jí)學(xué)術(shù)刊物如,Cell,Molecular Cell, eLife,PNAS等。本公司的管理團(tuán)隊(duì)均具備數(shù)十年國(guó)際制藥企業(yè)的管理經(jīng)驗(yàn),曾成功推動(dòng)多個(gè)藥物進(jìn)入臨床實(shí)驗(yàn)和上市使用。公司福利待遇:對(duì)于優(yōu)秀博士公司有機(jī)會(huì)解決北京戶口問題;公司設(shè)有博士后工作站。
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